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MD (Pharmacology), MBBS
Last updated
29 Nov 2023 | 06:56 PM (IST)
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Home>Iletin NPH>iletin nph 40iu/ml injection
Prescription Required
Marketer
Eli Lilly and Company India Pvt Ltd
SALT COMPOSITION
Insulin Isophane (40IU)
Salt Synonyms
NPH, Neutral protamine Hagedorn
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
Product introduction
Iletin NPH 40IU/ml Injection is used to improve blood sugar control in adults and children with type 1 and type 2 diabetes mellitus. It is an intermediate-acting type of insulin that helps to lower blood sugar levels and reduce the chances of developing serious complications of diabetes.
Iletin NPH 40IU/ml Injection is often prescribed along with short-acting insulin or other oral diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. Don’t stop taking it unless your doctor tells you to. It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.
The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it's important to always inject the correct dose of medicine only, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Repeated puncturing of the same site of the skin may lead to lipodystrophy (skin thickening or pits at the injection site). Some people may gain weight or develop edema (swelling over the whole body due to fluid retention) while taking insulin.
Do not use this medicine when you have low blood glucose levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.
Uses of Iletin NPH Injection
- Diabetes
Benefits of Iletin NPH Injection
In Diabetes
Iletin NPH 40IU/ml Injection is an intermediate-acting type of insulin that is usually used along with other diabetes medication for controlling blood sugar levels. It replaces the insulin that is normally produced in the body. This helps the glucose get into your muscle and fat cells so your body can use it for energy. It also decreases glucose production in the liver.
Lowering of blood sugar level helps reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Learn exactly how, where, and when to inject this insulin for it to be most effective. Take it regularly along with proper diet and exercise for a normal, healthy life.
Side effects of Iletin NPH Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Iletin NPH
- Hypoglycemia (low blood glucose level)
How to use Iletin NPH Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Iletin NPH Injection works
Iletin NPH 40IU/ml Injection is an intermediate-acting insulin, that starts working in 1-2 hours after injection. It works similar to the insulin that is produced by the body. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver. This helps to lower the blood sugar levels in diabetes mellitus.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Iletin NPH 40IU/ml Injection.
SAFE IF PRESCRIBED
Iletin NPH 40IU/ml Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Iletin NPH 40IU/ml Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Iletin NPH 40IU/ml Injection should be used with caution in patients with kidney disease. Dose adjustment of Iletin NPH 40IU/ml Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver
CAUTION
Iletin NPH 40IU/ml Injection should be used with caution in patients with liver disease. Dose adjustment of Iletin NPH 40IU/ml Injection may be needed. Please consult your doctor.
Regular monitoring of glucose levels is recommended for dose adjustment.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Iletin NPH 40IU/ml Injection
₹87.7/Injection
Eli Lilly and Company India Pvt Ltd
₹174/injection
92% costlier
Biocon
₹178/injection
97% costlier
Shreya Life Sciences Pvt Ltd
₹140.7/injection
55% costlier
Cadila Pharmaceuticals Ltd
₹152.25/injection
68% costlier
Sun Pharmaceutical Industries Ltd
₹143.42/injection
58% costlier
Quick tips
- Hypoglycemia (low blood sugar level) is a common side effect. Hence, regular monitoring of blood sugar levels is required while taking this medicine.
- Injection below the skin of the abdomen results in faster absorption than other injection sites.
Injection sites must be rotated to prevent hard lumps from developing at one site.
- Opened vials/cartridge are good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Fact Box
Chemical Class
Insulin analogue
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Human insulin- intermediate acting
Interaction with drugs
Taking Iletin NPH with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Benazepril
Brand(s)
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Apriace, Bampril, Benzil
Moderate
Captopril
Brand(s)
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Capotril, Capsuletopril, Aceten
Moderate
Enalapril
Brand(s)
:
Enatol, AB-Pril, Inopril
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Fosinopril
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Patient concerns
Several diabetes ,, highest diabetes
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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Please explain diabetes and diabetes diet
Dr. Sanjay Bhatt
Physician
Diabetes is a medical condition in which sugar, or glucose, levels build up in your bloodstream. There?s not enough insulin to move the sugar into your cells, which are where the sugar is used for energy. This causes your body to rely on alternative energy sources in your tissues, muscles, and organs. This is a chain reaction that can cause a variety of symptoms. Type 2 diabetes can develop slowly. The symptoms may be mild and easy to dismiss at first. The early symptoms may include: constant hunger a lack of energy fatigue weight loss excessive thirst frequent urination dry mouth itchy skin blurry visionDiet is an important tool to keep your heart healthy and blood sugar levels within a safe and healthy range. It doesn?t have to be complicated or unpleasant. The diet recommended for people with type 2 diabetes is the same diet just about everyone should follow. It boils down to a few key actions: Eat meals and snacks on schedule. Choose a variety of foods that are high in nutrition and low in empty calories. Be careful not to overeat. Read food labels closely.
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suffering form diabetes suffering form diabetes
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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medicine for diabetes ? Diabetes levelis 200+
Dr. Sanjay Bhatt
Physician
It is not good control. A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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Do I have diabetes? Do I have diabetes?
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Do fasting and pp
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I am suffering from diabetes type 1 diabetes .
Dr. Jagruti Mahendra Parikh
Diabetology
Type 1 diabetes are are ketosis prone insulin dependent type of types It is advisable some times to get your C.peptide levels and thyroid and s.insulin levels along with sonography of abdomen done to know wether you really have type -1 diabetes
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Best Madeline of diabetes .and best food chart in diabetes in Daley basis . Best excise diabetes.
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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Fasting 160 pp 230 recommend me diabetes medicine , I am taking diabetes tables. Diabetes for 20 year
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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FAQs
Q. How does biphasic isophane insulin work?
Insulin isophane is a recombinant human insulin analogue (genetically modified insulin that is grown in a laboratory and similar to human insulin). It is an intermediate acting insulin preparation. Insulin isophane acts by replacing the normal production of insulin and by helping transfer sugar from the blood into other body tissues where it is utilized to generate energy. It also stops the liver from producing more sugar. Intermediate acting insulin preparations start acting within an hour or 2 of injection, and reach a period of peak activity that lasts up to 7 hours, following which the action trails off; overall duration of action ranges from 18 to 24 hours.
Q. What is Iletin NPH 40IU/ml Injection? How is it made?
Iletin NPH 40IU/ml Injection is a man-made version of human insulin, produced by the process of biotechnology called recombinant DNA technology. It is sold as a sterile, aqueous, clear, and colorless solution that contains insulin aspart along with other constituents like glycerin, phenol, metacresol, zinc, sodium chloride etc.
Q. Can Iletin NPH 40IU/ml Injection cause hypoglycemia? How do I prevent it?
Yes. The most common side effect of Iletin NPH 40IU/ml Injection is hypoglycemia. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, don’t skip meals and be consistent in the timing and amount of your meals. Take some snacks as per your requirement if you over exercise. Regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you. Take all your medicines prescribed by the doctor on time and consult your doctor if you notice any fluctuations in your blood sugar levels.
Q. What are the other side effects of Iletin NPH 40IU/ml Injection? How to prevent them?
The other side effects of Iletin NPH 40IU/ml Injection are injection site reactions such as redness, itching, pain and swelling. However, these are temporary and usually resolve on their own. Rarely, it can also cause lipodystrophy, which means abnormal changes in the fat tissues due to repeated insulin injections in the same area of the skin. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.
Q. How should Iletin NPH 40IU/ml Injection be used?
Iletin NPH 40IU/ml Injection is injected under the skin (subcutaneously). Your doctor will show you the area of your skin where you should inject it. Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs, or upper arms. Never inject Humalog into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of the body, making sure to move around within that area with each injection, for one or two weeks.Then move to another area of your body and repeat the process. Use the same area for at least a week to avoid extreme blood sugar variations.
Q. Is Iletin NPH 40IU/ml Injection given as an injection into a vein (intravenous)?
Yes, sometimes, in specific situations like diabetic ketoacidosis, severe hyperglycemia etc, Iletin NPH 40IU/ml Injection may be given as an injection into a vein (intravenous). However, it is only given by a doctor, under continuous monitoring of blood sugar levels in a hospital setting.
Q. Is Iletin NPH 40IU/ml Injection safe to use in pregnancy?
Yes. Iletin NPH 40IU/ml Injection is safe to use in pregnancy if prescribed by a doctor. However, please inform your doctor if you are pregnant, planning to conceive or breastfeeding before using Iletin NPH 40IU/ml Injection. You may require dose modifications and your doctor will advise you to monitor your blood sugar levels regularly. You must follow the instructions of your doctor to get maximum benefit.
Q. When does the dosage of Iletin NPH 40IU/ml Injection need to be changed?
You should consult your doctor for dose adjustment if you experience weight gain or loss, increased stress, illness, changes in diet such as missed meals or if you are taking alcohol. Your dose may also change if you have recently changed your exercise regime or are taking any medicines. Also, you must be vigilant on the changes you experience while first using Iletin NPH 40IU/ml Injection. For eg, you may notice certain side effects that are usually temporary but if these are very severe, you may need dose modifications.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1251-53.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 733-34.
Human insulin. Bagsværd, Denmark: Novo Nordisk A/S; 2002 [18 Sep. 2007]. [Accessed 12 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
Marketer details
Name: Eli Lilly and Company India Pvt Ltd
Address: Plot# 92, Sector 32, Institutional Area, Gurgaon-122001, HARYANA, INDIA
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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