1. Soy isoflavone: The multipurpose phytochemical (Review) - PMC - NCBI
Jun 3, 2013 · Soy isoflavones are compounds found in soybean and soybean products. They have been reported to possess numerous physiological properties, ...
Soy isoflavones are compounds found in soybean and soybean products. They have been reported to possess numerous physiological properties, such as antitumor, anti-menopausal (female) osteoporosis and anti-aging. They have also been reported to ...
2. Soy Isoflavones | Linus Pauling Institute | Oregon State University
Soy isoflavones are known to have weak estrogenic or hormone-like activity due to their structural similarity with 17-β-estradiol.
Contents Summary Introduction Metabolism and Bioavailability Biological Activities Estrogenic and anti-estrogenic Estrogen receptor-independent Disease Prevention Hormone-associated ca
3. Scientific Evidence Supporting the Beneficial Effects of Isoflavones on ...
Dec 17, 2020 · The authors reported that isoflavone intake from soy products and legumes was associated with a 19% reduction in endometrial cancer risk.
Isoflavones are phenolic compounds with a chemical structure similar to that of estradiol. They are present in several vegetables, mainly in legumes such as soy, white and red clover, alfalfa and beans. The most significant food source of ...
4. [PDF] USDA Database for the Isoflavone Content of Selected Foods Release ...
Since soybeans are a major source of dietary isoflavones and soybeans and soybean products are also a good source of protein, inclusion of soy foods in the diet ...
5. Benefits and Risks of Taking Isoflavones - Verywell Health
Sep 28, 2024 · Isoflavones are plant-based compounds primarily found in soybeans that mimic the action of the hormone estrogen. Foods rich in isoflavones ...
Learn about the benefits and risks of taking isoflavones for menopausal symptoms, lowering the risk of cancer and osteoporosis, and cardiovascular health.
:max_bytes(150000):strip_icc()/isoflavones-benefits-side-effects-dosage-and-interactions-4687017-primary-recirc-73e50bf323144eb8961c7991e017db7b.jpg)
6. Effects of soybean isoflavone aglycone on osteoporosis in ...
Jun 4, 2023 · Some studies have confirmed that soybean isoflavone has estrogenic activity, and the main active component of soybean isoflavones is isoflavone ...
Postmenopausal osteoporosis is one of the most common metabolic diseases in old women, and supplementing estrogen through bioactive substances is one of the ...
7. Increase of isoflavones in the aglycone form in soybeans ... - Nature
Jul 17, 2019 · Isoflavones are naturally occurring group of phytoestrogens. They are mostly found among the members of the Fabaceae family, primarily soybeans ...
Isoflavones are a group of phytoestrogens, naturally-occurring substances important for their role in human health. Legumes, particularly soybeans (Glycine max (L.) Merr.), are the richest source of isoflavones in human diet. Since there is not much current data on genetics of isoflavones in soybean, particularly in the aglycone form, elucidation of the mode of inheritance is necessary in order to design an efficient breeding strategy for the development of high-isoflavone soybean genotypes. Based on the isoflavone content in 23 samples of soybeans from four different maturity groups (00, 0, I and II), three crosses were made in order to determine the inheritance pattern and increase the content of total isoflavones and their aglycone form. Genotype with the lowest total isoflavone content (NS-L-146) was crossed with the low- (NS Zenit), medium (NS Maximus), and high- (NS Virtus) isoflavone genotypes. There were no significant differences in the total isoflavone content (TIF) between F2 populations, and there was no transgression among genotypes within the populations. Each genotype within all three populations had a higher TIF value than the lower parent (NS-L-146), while genotypes with a higher TIF value than the better parent were found only in the NS-L-146 × NS Zenit cross. However, significant differences in the aglycone ratio (ratio of aglycone to glycone form of isoflavones) were found between the populations. The highest aglycone ratio was found in the NS-L-146 × NS M...
8. Selective Effects of Genistein, a Soybean Isoflavone, on B ...
These results indicate that genistein exhibits estrogenic action in bone and bone marrow, to regulate B-lymphopoiesis and prevent bone loss.
Abstract. Genistein, an isoflavone abundantly present in soybeans, has structural similarity to estrogen, suggesting that genistein may act as a phytoestro
9. Current Perspectives on the Beneficial Effects of Soybean Isoflavones and ...
They have been known to prevent and treat various diseases, including cardiovascular diseases, metabolic syndromes, osteoporosis, diabetes, brain-related ...
Soybeans are rich in proteins and lipids and have become a staple part of the human diet. Besides their nutritional excellence, they have also been shown to contain various functional components, including isoflavones, and have consequently received increasing attention as a functional food item. Isoflavones are structurally similar to 17-β-estradiol and bind to estrogen receptors (ERα and ERβ). The estrogenic activity of isoflavones ranges from a hundredth to a thousandth of that of estrogen itself. Isoflavones play a role in regulating the effects of estrogen in the human body, depending on the situation. Thus, when estrogen is insufficient, isoflavones perform the functions of estrogen, and when estrogen is excessive, isoflavones block the estrogen receptors to which estrogen binds, thus acting as an estrogen antagonist. In particular, estrogen antagonistic activity is important in the breast, endometrium, and prostate, and such antagonistic activity suppresses cancer occurrence. Genistein, an isoflavone, has cancer-suppressing effects on estrogen receptor-positive (ER+) cancers, including breast cancer. It suppresses the function of enzymes such as tyrosine protein kinase, mitogen-activated kinase, and DNA polymerase II, thus inhibiting cell proliferation and inducing apoptosis. Genistein is the most biologically active and potent isoflavone candidate for cancer prevention. Furthermore, among the various physiological functions of isoflavones, they are best known for thei...
10. Isoflavones: What They Are, Benefits, and Risks - ZOE
Mar 19, 2024 · Summary. Isoflavones are a type of polyphenol found in soy and soy products. Including isoflavones and other phytoestrogens in your diet may ...
What are isoflavones and should you be eating them? This article explains the benefits, risks, and ways to include them in your diet.
11. Soy Isoflavones Oral: Uses, Side Effects, Interactions ... - WebMD
Uses. Soy has been used to treat certain symptoms of menopause (such as hot flashes) and to help prevent bone loss (osteoporosis).Some supplement products have ...
Find patient medical information for Soy Isoflavones oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
